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NK 252 mass The presence of external NAD P H
2019-10-11
The presence of external NAD(P)H dehydrogenases (NDE) on the outer surface of the inner mitochondrial membrane enables the mitochondria to oxidize cytosolic NAD(P)H (Moller 2001). A porin (a voltage-dependent anion-selective channel, VDAC) that is abundant in the outer mitochondrial membrane permits
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Multiple protein species are known to naturally exist for
2019-10-11
Multiple protein species are known to naturally exist for the transmembrane receptors DDR1 and DDR2. Five splice variants have been characterized for DDR1 (“a” through “e”). The d and e isoforms lack the intracellular kinase domain of DDR1. The splicing of DDR1 to various extents has been reported i
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Herein we report the expression of shrimp Cdk
2019-10-11
Herein we report the expression of shrimp Cdk-2 in hepatopancreas, gills and muscle, finding higher expression in hepatopancreas and gills and lower expression in muscle. No significant changes due to hypoxia and hypoxia reoxygenation were detected on the expression of Cdk-2 in hepatopancreas and gi
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CD is a key co stimulation surface marker that can
2019-10-11
CD28 is a key co-stimulation surface marker that can be detected in all peripheral T Nicotine in newborns, and the proportion of CD28bearing T cells reduces progressively with age [reviewed by (Fagnoni et al., 1996; Weng et al., 2009)]. Therefore, CD28nullCD8+ T cells are one of the most acknowledge
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Present malarial chemotherapies mainly rely
2019-10-10
Present malarial chemotherapies mainly rely on a very few chemotypes or their allied structures such as quinolines, anti-folates and some cyclic endo-peroxides (Nayyar et al., 2012). Over the last few decades, the extensive and repetitive deployment of these drugs has stimulated resistance in the pa
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Agglutinin like sequence ALS gene is well characterized gene
2019-10-10
Agglutinin-like sequence (ALS) gene is well-characterized gene family in candidiasis due to its importance in pathogenicity of C albicans. Previously, C. albicans ALS1 gene product was reported as cell surface protein that mediates adherence to endothelial and epithelial igf ir in vitro and during b
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Acidic substituents showed moderate biochemical activity
2019-10-10
Acidic substituents () showed moderate biochemical activity, but these compounds showed reduced cellular potency. Additional compounds bearing a carboxylic CGS 21680 mass were also prepared and tested (data not shown). All of acidic compounds showed low cellular potency regardless of their biochemi
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Matrine Asteroids can provide an abundant supply of
2019-10-10
Asteroids can provide an abundant supply of other resources, such as carbon, nitrogen, or calcium compounds, but will only be useful once the space economy is sufficiently developed to provide economically interesting uses for them. Others, such as titanium or aluminium, also exist in asteroids, but
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SPR was used to measure biomolecular
2019-10-10
SPR was used to measure biomolecular kinetic interactions between TERRA G-quadruplex and ligand in the present study. SPR is a widely used method, but cannot tell which specific type of interaction happened. Compounds with similar structures probably have similar mechanism of interaction, while comp
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Other membrane currents are affected as
2019-10-10
Other membrane currents are affected as well. Some studies have provided evidence that sulfonylureas, in addition to blocking KATP channels, also inhibit chloride and calcium channels. GLYB has been shown to almost inhibit the current generated by Na+–K+ pumps in a concentration-dependent manner (wi
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br Experimental Procedures br Author Contributions M
2019-10-09
Experimental Procedures Author Contributions M.B., with input and help from T.T.H., conceived the project, designed and performed the experiments, analyzed the data, and wrote the manuscript. B.B.B. and F.D.M. synthesized the wild-type and (nonhydrolyzable, NH) Ub tetramers and contributed Fig
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N fowleri enters the host through the nasal
2019-10-09
N. fowleri enters the host through the nasal cavity and travels via the olfactory nerve into the Phosphatase Inhibitor Cocktail 1 (100X in DMSO) where it causes PAM (Visvesvara and Stehr-Green, 1990). The ameba most commonly infects healthy young adults and children and is able to evade the immune
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Several RNA BPs like the ELAV protein
2019-10-09
Several RNA-BPs, like the ELAV protein family member HuR, tristetraprolin (TTP) or the KH-type splicing regulatory protein (KSRP) have been shown to interact with these AREs and thereby lead to stabilization or destabilization of the mRNA [5]. Control of nucleocytoplasmic mRNA export is also very i
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Our conclusion is in disagreement with that of a recent
2019-10-09
Our conclusion is in disagreement with that of a recent paper by Park et al. [10], which suggests that nitric oxide (NO) inhibition of VHL recruitment occurs by nitrosylation of the 520 cysteine in HIF-1α, and that SNAP does not directly inhibit hydroxylation of HIF peptide by HPH-2. Although this d
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br Introduction The cervix is a poorly studied component
2019-10-09
Introduction The clofibrate pathway is a poorly studied component of the mare’s reproductive tract. It has anatomical and biological defense mechanisms involved in the delicate balance between immunological tolerance, sperm transport and biological defense. Anatomically, the cervix is composed of
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